Psoriasis is a chronic skin condition that manifests as scaly, red, inflamed and itchy patches that can cause considerable discomfort. The condition is considered a genetic disorder with five typical forms that occur in around 2% of the population. The most commonly observed form is plaque psoriasis which is characterized by scaly, red plaques that frequently occur on the knees, elbows and the scalp. A significant proportion of plaque psoriasis sufferers will develop psoriatic joints where inflammation creates an arthritis-like condition.
Modern medicine states that there is no cure and the causes are not well understood, however it is believed to be an auto-immune disorder triggered by environmental influences.
I, and members of my family, have endured plaque psoriasis on and off for quite some considerable time. During those years, numerous different doctors have attempted to control the condition with a wide array of pharmaceuticals, over-the-counter medications and natural remedies with limited success or risks of significant side-effects. With my background in biochemistry and a strong interest in natural medicine, I decided to carry out my own research and try to formulate my own concoction. I spent many, many hours trawling through the PubMed database (http://www.ncbi.nlm.nih.gov/pubmed) and this is a list of some of the research that piqued my interest…
If you are not interested in the research then please skip this section !
PMID 20212509 Topical isoflavonoids reduce experimental cutaneous inflammation in mice.
PMID 20221619 Control of cutaneous antimicrobial peptides by vitamin D3.
PMID 20218931 Itk inhibitors: a patent review.
PMID 20192957 Psoriasis and extra domain A fibronectin loops.
PMID 20188517 Neutrophil-dominant psoriasis-like skin inflammation induced by epidermal-specific expression of Raf in mice.
PMID 20173395 The first decade of biologic TNF antagonists in clinical practice: lessons learned, unresolved issues and future directions.
PMID 20171437 The role of dendritic cells in auto-inflammation seen in psoriasis.
PMID 20163421 1,24-Dihydroxyvitamin D₃ (tacalcitol) prevents skin T-cell infiltration.
PMID 20128791 Interleukin-1 from epithelial cells fosters T cell-dependent skin inflammation.
PMID 20074471 Proinflammatory cytokine production in HaCaT cells treated by eosin: implications for the topical treatment of psoriasis.
PMID 19459144 Potential skin antiinflammatory effects of 4-methylthiobutylisothiocyanate (MTBI) isolated from rocket (Eruca sativa) seeds.
PMID 19383492 Study on the levels of trace elements in mild and severe psoriasis.
PMID 19218914 Aloe vera in dermatology: a brief review.
This list is far from exhaustive, but the possible mode of action by which plaque psoriasis impacts the epidermis was becoming clearer to me. More importantly, from this new understanding I was better equipped to research natural compounds that could negate these objectionable activities. Following more lengthy investigation, including analysis of Western, Traditional Chinese, Orthomolecular and Natural medical systems, I settled on a blend of botanical and orthomolecular ingredients. All components selected were natural, and free of synthetics and pharmaceuticals. I had high hopes and was eager to test my theories.
To cut a long story short, I found that the optimum blend was a mixture of dry powders and filtered water that was delivered to the skin as a ‘mudpack’ of sorts. My results were amazing. A smaller test patch (several square inches) was diminished in a few days and completely eradicated after a couple of weeks of continuous application. My method of application was to apply the ‘mud’ prior to sleep and cover it with a piece of gauze. The following morning the mud was washed off and the area moisturized with petroleum jelly, aloe vera or coconut oil. A pleasant surprise was that the plaque did not reappear after treatment was discontinued. The only way the plaque would return was following trauma to the original area that broke the skin and prompted bleeding. Thereafter, another cycle of treatment, once the broken skin was healed, would reverse the psoriasis breakout once again.
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